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Apc gene suppresses intracranial aneurysm formation and rupture through inhibiting the NF-κB signaling pathway mediated inflammatory response
Background: Intracranial aneurysm (IA) is a critical acquired cerebrovascular disease that may cause subarachnoid hemorrhage, and nuclear factor-κB (NF-κB)-mediated inflammation is involved in the pathogenesis of IA. Adenomatous polyposis coli (Apc) gene is a tumor suppressor gene associated with bo...
Autores principales: | Lai, Xian-Liang, Deng, Zhi-Feng, Zhu, Xin-Gen, Chen, Zhi-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434386/ https://www.ncbi.nlm.nih.gov/pubmed/30808715 http://dx.doi.org/10.1042/BSR20181909 |
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