Hypoxia-induced pulmonary hypertension and chronic lung disease: caveolin-1 dysfunction an important underlying feature

Caveolin-1 (cav-1) has been shown to play a significant role in the pathogenesis of pulmonary hypertension (PH). In the monocrotaline model of PH, the loss of endothelial cav-1 as well as reciprocal activation of proliferative and anti-apoptotic pathways initiate the disease process and facilitate i...

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Detalles Bibliográficos
Autores principales: Huang, Jing, Frid, Maria, Gewitz, Michael H., Fallon, John T., Brown, Dale, Krafsur, Greta, Stenmark, Kurt, Mathew, Rajamma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434444/
https://www.ncbi.nlm.nih.gov/pubmed/30806156
http://dx.doi.org/10.1177/2045894019837876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434444/
https://www.ncbi.nlm.nih.gov/pubmed/30806156
http://dx.doi.org/10.1177/2045894019837876

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