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Novel Bivalent and D-Peptide Ligands of CXCR4 Mobilize Hematopoietic Progenitor Cells to the Blood in C3H/HeJ Mice

The interaction of SDF-1α (also known as CXCL12) with the CXCR4 receptor plays a critical role in the retention of hematopoietic stem cells (HSCs) in bone marrow. The viral macrophage inflammatory protein-II (vMIP-II), a human herpesvirus-8 (HHV-8)-encoded viral chemokine, can bind the CXCR4 recepto...

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Detalles Bibliográficos
Autores principales: Mao, Yujia, Meng, Qian, Song, Panpan, Zhu, Siyu, Xu, Yan, Snyder, Evan Y., An, Jing, Huang, Ziwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434473/
https://www.ncbi.nlm.nih.gov/pubmed/29991278
http://dx.doi.org/10.1177/0963689718784957