The effect of neoadjuvant platinum-based chemotherapy in BRCA mutated triple negative breast cancers -systematic review and meta-analysis

BACKGROUND: Triple negative breast cancers (TNBC) are associated with an aggressive clinical course, earlier recurrence and short survival. BRCA – mutated tumours represent up to 25% of all TNBC. BRCA status is being studied as a predictive biomarker of response to platinum agents. However, the pred...

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Detalles Bibliográficos
Autores principales: Caramelo, Olga, Silva, Cristina, Caramelo, Francisco, Frutuoso, Cristina, Almeida-Santos, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434625/
https://www.ncbi.nlm.nih.gov/pubmed/30962858
http://dx.doi.org/10.1186/s13053-019-0111-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434625/
https://www.ncbi.nlm.nih.gov/pubmed/30962858
http://dx.doi.org/10.1186/s13053-019-0111-y

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