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Functional characterization of the cytochrome P450 monooxygenase CYP71AU87 indicates a role in marrubiin biosynthesis in the medicinal plant Marrubium vulgare

BACKGROUND: Horehound (Marrubium vulgare) is a medicinal plant whose signature bioactive compounds, marrubiin and related furanoid diterpenoid lactones, have potential applications for the treatment of cardiovascular diseases and type II diabetes. Lack of scalable plant cultivation and the complex m...

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Detalles Bibliográficos
Autores principales: Karunanithi, Prema S., Dhanota, Puja, Addison, J. Bennett, Tong, Shen, Fiehn, Oliver, Zerbe, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434833/
https://www.ncbi.nlm.nih.gov/pubmed/30909879
http://dx.doi.org/10.1186/s12870-019-1702-5