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Reduced transient receptor potential vanilloid 2 expression in alveolar macrophages causes COPD in mice through impaired phagocytic activity

BACKGROUND: Defective phagocytosis in alveolar macrophages is associated with chronic obstructive pulmonary disease (COPD). Transient receptor potential cation channel subfamily V member 2 (TRPV2), a type of nonselective cation channel pertinent to diverse physiological functions, regulates macropha...

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Detalles Bibliográficos
Autores principales: Masubuchi, Hiroaki, Ueno, Manabu, Maeno, Toshitaka, Yamaguchi, Koichi, Hara, Kenichiro, Sunaga, Hiroaki, Matsui, Hiroki, Nagasawa, Masahiro, Kojima, Itaru, Iwata, Yuko, Wakabayashi, Shigeo, Kurabayashi, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434859/
https://www.ncbi.nlm.nih.gov/pubmed/30914062
http://dx.doi.org/10.1186/s12890-019-0821-y