CDK7 inhibitor suppresses tumor progression through blocking the cell cycle at the G2/M phase and inhibiting transcriptional activity in cervical cancer

BACKGROUND: The disordered cell cycle and dysregulated expression of numerous oncogenes involved in tumor-relevant processes are highly related to the tumorigenesis of cervical cancer. Cyclin-dependent kinase 7 (CDK7) constitutes the indispensable catalytic subunit of CDK-activating kinase (CAK), wh...

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Detalles Bibliográficos
Autores principales: Zhong, Shanshan, Zhang, Yi, Yin, Xia, Di, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434917/
https://www.ncbi.nlm.nih.gov/pubmed/30962695
http://dx.doi.org/10.2147/OTT.S195655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434917/
https://www.ncbi.nlm.nih.gov/pubmed/30962695
http://dx.doi.org/10.2147/OTT.S195655

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