The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and hemostasis

ESSENTIALS: Heat shock protein 47 (HSP47), a collagen specific chaperone is present on the platelet surface. Collagen mediated platelet function was reduced following blockade or deletion of HSP47. GPVI receptor regulated signalling was reduced in HSP47 deficient platelets. Platelet HSP47 tethers to...

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Detalles Bibliográficos
Autores principales: Sasikumar, P., AlOuda, K. S., Kaiser, W. J., Holbrook, L. M., Kriek, N., Unsworth, A. J., Bye, A. P., Sage, T., Ushioda, R., Nagata, K., Farndale, R. W., Gibbins, J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434988/
https://www.ncbi.nlm.nih.gov/pubmed/29512284
http://dx.doi.org/10.1111/jth.13998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434988/
https://www.ncbi.nlm.nih.gov/pubmed/29512284
http://dx.doi.org/10.1111/jth.13998

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