Foxp3(+) Regulatory and Conventional CD4(+) T Cells Display Similarly High Frequencies of Alloantigen-Reactive Cells

Foxp3(+) regulatory T cells (Tregs) play a major role in acquired immune tolerance to allogenic transplants. Their suppressive activity is thought to require T cell receptor (TCR)-driven antigen recognition; little, however, is known about the fraction of Tregs able to recognize alloantigens within...

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Detalles Bibliográficos
Autores principales: Lalfer, Mélanie, Chappert, Pascal, Carpentier, Maxime, Urbain, Dominique, Davoust, Jean M., Gross, David-Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434998/
https://www.ncbi.nlm.nih.gov/pubmed/30941146
http://dx.doi.org/10.3389/fimmu.2019.00521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434998/
https://www.ncbi.nlm.nih.gov/pubmed/30941146
http://dx.doi.org/10.3389/fimmu.2019.00521

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