Cargando…

NGS based haplotype assembly using matrix completion

We apply matrix completion methods for haplotype assembly from NGS reads to develop the new HapSVT, HapNuc, and HapOPT algorithms. This is performed by applying a mathematical model to convert the reads to an incomplete matrix and estimating unknown components. This process is followed by quantizing...

Descripción completa

Detalles Bibliográficos
Autores principales: Majidian, Sina, Kahaei, Mohammad Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435133/
https://www.ncbi.nlm.nih.gov/pubmed/30913270
http://dx.doi.org/10.1371/journal.pone.0214455