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Single particle trajectories reveal active Endoplasmic Reticulum luminal flow

The Endoplasmic Reticulum (ER), a network of membranous sheets and pipes, supports functions encompassing biogenesis of secretory proteins and delivery of functional solutes throughout the cell1,2. Molecular mobility through the ER network enables these functionalities, but diffusion alone is not su...

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Detalles Bibliográficos
Autores principales: Holcman, David, Parutto, Pierre, Chambers, Joseph E., Fantham, Marcus, Young, Laurence J., Marciniak, Stefan J., Kaminski, Clemens F., Ron, David, Avezov, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435195/
https://www.ncbi.nlm.nih.gov/pubmed/30224760
http://dx.doi.org/10.1038/s41556-018-0192-2