Nutritional stress targets LeishIF4E-3 to storage granules that contain RNA and ribosome components in Leishmania

Leishmania parasites lack pathways for de novo purine biosynthesis. The depletion of purines induces differentiation into virulent metacyclic forms. In vitro, the parasites can survive prolonged periods of purine withdrawal changing their morphology to long and slender cells with an extended flagell...

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Detalles Bibliográficos
Autores principales: Shrivastava, Rohit, Drory-Retwitzer, Matan, Shapira, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435199/
https://www.ncbi.nlm.nih.gov/pubmed/30870425
http://dx.doi.org/10.1371/journal.pntd.0007237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435199/
https://www.ncbi.nlm.nih.gov/pubmed/30870425
http://dx.doi.org/10.1371/journal.pntd.0007237

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