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Leaky expression of channelrhodopsin-2 (ChR2) in Ai32 mouse lines

Optogenetics enables the selective activation of genetically-targeted neuronal populations using light-sensitive ion channels. Genetic strategies using Cre-dependent mouse strains, especially the Ai32 line expressing Channelrhodopsin (ChR2)-EYFP fusion protein, have been a popular means to drive ops...

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Detalles Bibliográficos
Autores principales: Prabhakar, Arthi, Vujovic, Dragan, Cui, Lian, Olson, William, Luo, Wenqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435231/
https://www.ncbi.nlm.nih.gov/pubmed/30913225
http://dx.doi.org/10.1371/journal.pone.0213326