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Human and Extracellular DNA Depletion for Metagenomic Analysis of Complex Clinical Infection Samples Yields Optimized Viable Microbiome Profiles

Metagenomic sequencing is a promising approach for identifying and characterizing organisms and their functional characteristics in complex, polymicrobial infections, such as airway infections in people with cystic fibrosis. These analyses are often hampered, however, by overwhelming quantities of h...

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Detalles Bibliográficos
Autores principales: Nelson, Maria T., Pope, Christopher E., Marsh, Robyn L., Wolter, Daniel J., Weiss, Eli J., Hager, Kyle R., Vo, Anh T., Brittnacher, Mitchell J., Radey, Matthew C., Hayden, Hillary S., Eng, Alexander, Miller, Samuel I., Borenstein, Elhanan, Hoffman, Lucas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435281/
https://www.ncbi.nlm.nih.gov/pubmed/30784601
http://dx.doi.org/10.1016/j.celrep.2019.01.091