Administration of Dexmedetomidine inhibited NLRP3 inflammasome and microglial cell activities in hippocampus of traumatic brain injury rats

The abnormally high nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain containing 3 (NLRP3) inflammasome activity is a typical characteristic of traumatic brain injury (TBI). Dexmedetomidine (Dex) is a highly selective α-2 adrenergic receptor agonist that inhibits the...

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Detalles Bibliográficos
Autores principales: Zheng, Bin, Zhang, Shuncai, Ying, Yanlu, Guo, Xinying, Li, Hengchang, Xu, Lixin, Ruan, Xiangcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435454/
https://www.ncbi.nlm.nih.gov/pubmed/30232232
http://dx.doi.org/10.1042/BSR20180892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435454/
https://www.ncbi.nlm.nih.gov/pubmed/30232232
http://dx.doi.org/10.1042/BSR20180892

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