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Advanced iron-overload cardiomyopathy in a genetic murine model is rescued by resveratrol therapy

Iron-overload cardiomyopathy is prevalent on a worldwide basis and is a major comorbidity in patients with genetic hemochromatosis and secondary iron overload. Therapies are limited in part due to lack of a valid preclinical model, which recapitulates advanced iron-overload cardiomyopathy. Male hemo...

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Detalles Bibliográficos
Autores principales: Das, Subhash K., Zhabyeyev, Pavel, Basu, Ratnadeep, Patel, Vaibhav B., Dyck, Jason R.B., Kassiri, Zamaneh, Oudit, Gavin Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435471/
https://www.ncbi.nlm.nih.gov/pubmed/29208771
http://dx.doi.org/10.1042/BSR20171302