Cysteine modifiers suggest an allosteric inhibitory site on the CAL PDZ domain

Protein–protein interactions have become attractive targets for both experimental and therapeutic interventions. The PSD-95/Dlg1/ZO-1 (PDZ) domain is found in a large family of eukaryotic scaffold proteins that plays important roles in intracellular trafficking and localization of many target protei...

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Detalles Bibliográficos
Autores principales: Zhao, Yu, Cushing, Patrick R., Smithson, David C., Pellegrini, Maria, Pletnev, Alexandre A., Al-Ayyoubi, Sahar, Grassetti, Andrew V., Gerber, Scott A., Guy, R. Kiplin, Madden, Dean R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435542/
https://www.ncbi.nlm.nih.gov/pubmed/29472314
http://dx.doi.org/10.1042/BSR20180231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435542/
https://www.ncbi.nlm.nih.gov/pubmed/29472314
http://dx.doi.org/10.1042/BSR20180231

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