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Galectin 3 inhibition attenuates renal injury progression in cisplatin-induced nephrotoxicity

Nephrotoxicity is a major toxic effect in chemotherapy, which constitutes up to 60% of hospitalized acute kidney injury (AKI). Very few treatment options exist to slow the transition from AKI to subsequent chronic kidney diseases (CKD). Here, we demonstrate that galectin-3 (Gal-3), a β-galactoside b...

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Detalles Bibliográficos
Autores principales: Li, Hong-yan, Yang, Shen, Li, Jing-chun, Feng, Jian-xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435560/
https://www.ncbi.nlm.nih.gov/pubmed/30455396
http://dx.doi.org/10.1042/BSR20181803