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Hydralazine Protects Nigrostriatal Dopaminergic Neurons From MPP(+) and MPTP Induced Neurotoxicity: Roles of Nrf2-ARE Signaling Pathway

Although the pathogenic mechanisms of Parkinson's disease (PD) remain unclear, ample empirical evidence suggests that oxidative stress is involved in the pathogenesis of this disease. The nuclear factor E2-related factor 2 (Nrf2) is known to activate several antioxidant response element (ARE)-d...

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Detalles Bibliográficos
Autores principales: Guo, Xingfang, Han, Chao, Ma, Kai, Xia, Yun, Wan, Fang, Yin, Sijia, Kou, Liang, Sun, Yadi, Wu, Jiawei, Hu, Junjie, Huang, Jinsha, Xiong, Nian, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435581/
https://www.ncbi.nlm.nih.gov/pubmed/30949126
http://dx.doi.org/10.3389/fneur.2019.00271