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Pleiotropic Effects of IL-33 on CD4(+) T Cell Differentiation and Effector Functions

IL-33, a member of the IL-1 family of cytokines, was originally described in 2005 as a promoter of type 2 immune responses. However, recent evidence reveals a more complex picture. This cytokine is released locally as an alarmin upon cellular damage where innate cell types respond to IL-33 by modula...

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Detalles Bibliográficos
Autores principales: Alvarez, Fernando, Fritz, Jörg H., Piccirillo, Ciriaco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435597/
https://www.ncbi.nlm.nih.gov/pubmed/30949175
http://dx.doi.org/10.3389/fimmu.2019.00522