MiR-424-3p suppresses galectin-3 expression and sensitizes ovarian cancer cells to cisplatin

PURPOSE: Assessment of miR-424-3p mimic capability to sensitize SK-OV-3 and TOV-21G ovarian cancer cells to cisplatin by decreasing the expression of galectin-3, which is an anti-apoptotic protein overexpressed in ovarian cancer and associated with resistance to chemotherapy. METHODS: We performed a...

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Detalles Bibliográficos
Autores principales: Bieg, Dominik, Sypniewski, Daniel, Nowak, Ewa, Bednarek, Ilona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Gynecologic Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435611/
https://www.ncbi.nlm.nih.gov/pubmed/30585294
http://dx.doi.org/10.1007/s00404-018-4999-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435611/
https://www.ncbi.nlm.nih.gov/pubmed/30585294
http://dx.doi.org/10.1007/s00404-018-4999-7

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