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Endothelial prostacyclin protects the kidney from ischemia-reperfusion injury

Prostacyclin, or PGI(2), is a product of PGI synthase (PGIS), down-stream of cyclooxygenase pathway. PGI(2) has been demonstrated to play an important role in maintaining renal blood flow. Non-steroidal anti-inflammatory drugs (NSAIDs) that inhibit cyclooxygenase are reported to increase the suscept...

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Detalles Bibliográficos
Autores principales: Cao, Yingxue, Guan, Yi, Xu, Yun-Yu, Hao, Chuan-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435627/
https://www.ncbi.nlm.nih.gov/pubmed/30413885
http://dx.doi.org/10.1007/s00424-018-2229-6