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High glucose level and angiotensin II type 1 receptor stimulation synergistically amplify oxidative stress in renal mesangial cells

Oxidative stress in renal mesangial cell causes diabetic glomerular changes. High glucose levels and angiotensin II (Ang II) are known to stimulate superoxide production in renal mesangial cells. However, it has been unclear whether Ang II stimulation and pre-conditioning with high glucose affects t...

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Detalles Bibliográficos
Autores principales: Akaishi, Tetsuya, Abe, Michiaki, Okuda, Hiroshi, Ishizawa, Kota, Abe, Takaaki, Ishii, Tadashi, Ito, Sadayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435641/
https://www.ncbi.nlm.nih.gov/pubmed/30914692
http://dx.doi.org/10.1038/s41598-019-41536-z