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High glucose level and angiotensin II type 1 receptor stimulation synergistically amplify oxidative stress in renal mesangial cells
Oxidative stress in renal mesangial cell causes diabetic glomerular changes. High glucose levels and angiotensin II (Ang II) are known to stimulate superoxide production in renal mesangial cells. However, it has been unclear whether Ang II stimulation and pre-conditioning with high glucose affects t...
Autores principales: | Akaishi, Tetsuya, Abe, Michiaki, Okuda, Hiroshi, Ishizawa, Kota, Abe, Takaaki, Ishii, Tadashi, Ito, Sadayoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435641/ https://www.ncbi.nlm.nih.gov/pubmed/30914692 http://dx.doi.org/10.1038/s41598-019-41536-z |
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