Utilization of NGS technologies to investigate transcriptomic and epigenomic mechanisms in trastuzumab resistance

NGS (Next Generation Sequencing) technologies allows us to determine key gene expression signatures that correlate with resistance (and responsiveness) to anti-cancer therapeutics. We have undertaken a transcriptomic and chromatin immunoprecipitation followed by sequencing (ChIP-seq) approach to des...

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Detalles Bibliográficos
Autores principales: Nava, Miguel, Dutta, Pranabananda, Farias-Eisner, Robin, Vadgama, Jaydutt V., Wu, Yanyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435657/
https://www.ncbi.nlm.nih.gov/pubmed/30914750
http://dx.doi.org/10.1038/s41598-019-41672-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435657/
https://www.ncbi.nlm.nih.gov/pubmed/30914750
http://dx.doi.org/10.1038/s41598-019-41672-6

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