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Improving in-silico normalization using read weights

Specialized de novo assemblers for diverse datatypes have been developed and are in widespread use for the analyses of single-cell genomics, metagenomics and RNA-seq data. However, assembly of large sequencing datasets produced by modern technologies is challenging and computationally intensive. In-...

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Detalles Bibliográficos
Autores principales: Durai, Dilip A., Schulz, Marcel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435659/
https://www.ncbi.nlm.nih.gov/pubmed/30914698
http://dx.doi.org/10.1038/s41598-019-41502-9