Low survival rate and muscle fiber-dependent aging effects in the McArdle disease mouse model

McArdle disease is an autosomal recessive disorder caused by the absence of the muscle glycogen phosphorylase, which leads to impairment of glycogen breakdown. The McArdle mouse, a model heavily affected by glycogen accumulation and exercise intolerance, was used to characterize disease progression...

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Detalles Bibliográficos
Autores principales: Real-Martinez, Alberto, Brull, Astrid, Huerta, Jordi, Tarrasó, Guillermo, Lucia, Alejandro, Martin, Miguel Angel, Arenas, Joaquin, Andreu, Antoni L., Nogales-Gadea, Gisela, Vissing, John, Krag, Thomas O., de Luna, Noemi, Pinós, Tomàs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435661/
https://www.ncbi.nlm.nih.gov/pubmed/30914683
http://dx.doi.org/10.1038/s41598-019-41414-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435661/
https://www.ncbi.nlm.nih.gov/pubmed/30914683
http://dx.doi.org/10.1038/s41598-019-41414-8

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