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Synergy between the alteration in the N-terminal region of butyrylcholinesterase K variant and apolipoprotein E4 in late-onset Alzheimer’s disease

While the life expectancy of the population has increased, Alzheimer’s disease (AD) has emerged as one of the greatest health problems of old age. AD is characterized by neuronal loss and cognitive decline. In the AD brain, there is a decrease in levels of acetylcholinesterase (AChE) and an increase...

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Detalles Bibliográficos
Autores principales: Jasiecki, Jacek, Limon-Sztencel, Anna, Żuk, Monika, Chmara, Magdalena, Cysewski, Dominik, Limon, Janusz, Wasąg, Bartosz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435664/
https://www.ncbi.nlm.nih.gov/pubmed/30914707
http://dx.doi.org/10.1038/s41598-019-41578-3