Cargando…
IL-4 together with IL-1β induces antitumor Th9 cell differentiation in the absence of TGF-β signaling
IL-9-producing CD4(+) (Th9) cells are a subset of CD4(+) T-helper cells that are endowed with powerful antitumor capacity. Both IL-4 and TGF-β have been reported to be indispensable for Th9 cell-priming and differentiation. Here we show, by contrast, that Th9 cell development can occur in the absenc...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435687/ https://www.ncbi.nlm.nih.gov/pubmed/30914642 http://dx.doi.org/10.1038/s41467-019-09401-9 |