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Context-dependent activity of A domains in the tyrocidine synthetase

Non-ribosomal peptide synthetases (NRPSs) are large, modular enzymes that produce bioactive peptides of tremendous structural and chemical diversity, due to the incorporation, alongside the canonical 20 amino acids, of non-proteinogenic amino acids, fatty acids, sugars and heterocyclic rings. For li...

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Detalles Bibliográficos
Autores principales: Degen, Anna, Mayerthaler, Florian, Mootz, Henning D., Di Ventura, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435693/
https://www.ncbi.nlm.nih.gov/pubmed/30914767
http://dx.doi.org/10.1038/s41598-019-41492-8