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Improved survival prognostication of node-positive malignant melanoma patients utilizing shotgun proteomics guided by histopathological characterization and genomic data

Metastatic melanoma is one of the most common deadly cancers, and robust biomarkers are still needed, e.g. to predict survival and treatment efficiency. Here, protein expression analysis of one hundred eleven melanoma lymph node metastases using high resolution mass spectrometry is coupled with in-d...

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Detalles Bibliográficos
Autores principales: Betancourt, Lazaro Hiram, Pawłowski, Krzysztof, Eriksson, Jonatan, Szasz, A. Marcell, Mitra, Shamik, Pla, Indira, Welinder, Charlotte, Ekedahl, Henrik, Broberg, Per, Appelqvist, Roger, Yakovleva, Maria, Sugihara, Yutaka, Miharada, Kenichi, Ingvar, Christian, Lundgren, Lotta, Baldetorp, Bo, Olsson, Håkan, Rezeli, Melinda, Wieslander, Elisabet, Horvatovich, Peter, Malm, Johan, Jönsson, Göran, Marko-Varga, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435712/
https://www.ncbi.nlm.nih.gov/pubmed/30914758
http://dx.doi.org/10.1038/s41598-019-41625-z