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Characteristics and homogeneity of N6-methylation in human genomes

A novel DNA modification, N-6 methylated deoxyadenosine (m6dA), has recently been discovered in eukaryotic genomes. Despite its low abundance in eukaryotes, m6dA is implicated in human diseases such as cancer. It is therefore important to precisely identify and characterize m6dA in the human genome....

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Detalles Bibliográficos
Autores principales: Pacini, Clare E., Bradshaw, Charles R., Garrett, Nigel J., Koziol, Magdalena J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435722/
https://www.ncbi.nlm.nih.gov/pubmed/30914725
http://dx.doi.org/10.1038/s41598-019-41601-7