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Antrodia cinnamomea induces anti-tumor activity by inhibiting the STAT3 signaling pathway in lung cancer cells

We examined the effects of an Antrodia cinnamomea ethanol extract (ACEE) on lung cancer cells in vitro and tumor growth in vivo. ACEE produced dose-dependent cytotoxic effects and induced apoptosis in Lewis lung carcinoma (LLC) cells. ACEE treatment increased expression of p53 and Bax, as well as cl...

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Detalles Bibliográficos
Autores principales: Huang, Tsung-Teng, Lan, Ying-Wei, Chen, Chuan-Mu, Ko, Yun-Fei, Ojcius, David M., Martel, Jan, Young, John D., Chong, Kowit-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435735/
https://www.ncbi.nlm.nih.gov/pubmed/30914735
http://dx.doi.org/10.1038/s41598-019-41653-9