Gut Microbiota-Based Pharmacokinetics and the Antidepressant Mechanism of Paeoniflorin

Paeoniflorin, the main component of Xiaoyao Wan, presents low oral bioavailability and unclear antidepressant mechanism. To elucidate the potential reasons for the low bioavailability of paeoniflorin and explore its antidepressant mechanism from the perspective of the gut microbiota, here, a chronic...

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Detalles Bibliográficos
Autores principales: Yu, Jin-Bo, Zhao, Zhen-Xiong, Peng, Ran, Pan, Li-Bin, Fu, Jie, Ma, Shu-Rong, Han, Pei, Cong, Lin, Zhang, Zheng-Wei, Sun, Li-Xin, Jiang, Jian-Dong, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435784/
https://www.ncbi.nlm.nih.gov/pubmed/30949054
http://dx.doi.org/10.3389/fphar.2019.00268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435784/
https://www.ncbi.nlm.nih.gov/pubmed/30949054
http://dx.doi.org/10.3389/fphar.2019.00268

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