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Theoretical analysis on thermodynamic stability of chignolin

Understanding the dominant factor in thermodynamic stability of proteins remains an open challenge. Kauzmann’s hydrophobic interaction hypothesis, which considers hydrophobic interactions between nonpolar groups as the dominant factor, has been widely accepted for about sixty years and attracted man...

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Detalles Bibliográficos
Autores principales: Sumi, Tomonari, Koga, Kenichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435801/
https://www.ncbi.nlm.nih.gov/pubmed/30914684
http://dx.doi.org/10.1038/s41598-019-41518-1