Distinct mechanical properties in homologous spectrin-like repeats of utrophin

Patients with Duchenne muscular dystrophy (DMD) lack the protein dystrophin, which is a critical molecular component of the dystrophin-glycoprotein complex (DGC). Dystrophin is hypothesized to function as a molecular shock absorber that mechanically stabilizes the sarcolemma of striated muscle throu...

Descripción completa

Detalles Bibliográficos
Autores principales: Rajaganapathy, Sivaraman, McCourt, Jackie L., Ghosal, Sayan, Lindsay, Angus, McCourt, Preston M., Lowe, Dawn A., Ervasti, James M., Salapaka, Murti V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435810/
https://www.ncbi.nlm.nih.gov/pubmed/30914715
http://dx.doi.org/10.1038/s41598-019-41569-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435810/
https://www.ncbi.nlm.nih.gov/pubmed/30914715
http://dx.doi.org/10.1038/s41598-019-41569-4

Ejemplares similares