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Distinct mechanical properties in homologous spectrin-like repeats of utrophin
Patients with Duchenne muscular dystrophy (DMD) lack the protein dystrophin, which is a critical molecular component of the dystrophin-glycoprotein complex (DGC). Dystrophin is hypothesized to function as a molecular shock absorber that mechanically stabilizes the sarcolemma of striated muscle throu...
Autores principales: | Rajaganapathy, Sivaraman, McCourt, Jackie L., Ghosal, Sayan, Lindsay, Angus, McCourt, Preston M., Lowe, Dawn A., Ervasti, James M., Salapaka, Murti V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435810/ https://www.ncbi.nlm.nih.gov/pubmed/30914715 http://dx.doi.org/10.1038/s41598-019-41569-4 |
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