Independent Microevolution Mediated by Mobile Genetic Elements of Individual Clostridium difficile Isolates from Clade 4 Revealed by Whole-Genome Sequencing

Horizontal gene transfer of mobile genetic elements (MGEs) accounts for the mosaic genome of Clostridium difficile, leading to acquisition of new phenotypes, including drug resistance and reconstruction of the genomes. MGEs were analyzed according to the whole-genome sequences of 37 C. difficile iso...

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Detalles Bibliográficos
Autores principales: Wu, Yuan, Liu, Chen, Li, Wen-Ge, Xu, Jun-Li, Zhang, Wen-Zhu, Dai, Yi-Fei, Lu, Jin-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435816/
https://www.ncbi.nlm.nih.gov/pubmed/30944881
http://dx.doi.org/10.1128/mSystems.00252-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435816/
https://www.ncbi.nlm.nih.gov/pubmed/30944881
http://dx.doi.org/10.1128/mSystems.00252-18

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