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Bleomycin Inhibits Proliferation via Schlafen-Mediated Cell Cycle Arrest in Mouse Alveolar Epithelial Cells

BACKGROUND: Idiopathic pulmonary fibrosis involves irreversible alveolar destruction. Although alveolar epithelial type II cells are key functional participants within the lung parenchyma, how epithelial cells are affected upon bleomycin (BLM) exposure remains unknown. In this study, we determined w...

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Detalles Bibliográficos
Autores principales: Jang, Soojin, Ryu, Se Min, Lee, Jooyeon, Lee, Hanbyeol, Hong, Seok-Ho, Ha, Kwon-Soo, Park, Won Sun, Han, Eun-Taek, Yang, Se-Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Tuberculosis and Respiratory Diseases 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435923/
https://www.ncbi.nlm.nih.gov/pubmed/29926548
http://dx.doi.org/10.4046/trd.2017.0124