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Hemozoin‐induced activation of human monocytes toward M2‐like phenotype is partially reversed by antimalarial drugs—chloroquine and artemisinin

Plasmodium falciparum malaria is the most severe form of malaria with several complications. The malaria pigment‐hemozoin (Hz) is associated with severe anemia, cytokine dysfunction, and immunosuppression, thus making it an interesting target for developing new strategies for antimalarial therapy. M...

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Detalles Bibliográficos
Autores principales: Bobade, Deepali, Khandare, Ashwin V., Deval, Mangesh, Shastry, Padma, Deshpande, Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436431/
https://www.ncbi.nlm.nih.gov/pubmed/29877619
http://dx.doi.org/10.1002/mbo3.651