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Decreased Ficolin-3-mediated Complement Lectin Pathway Activation and Alternative Pathway Amplification During Bacterial Infections in Patients With Type 2 Diabetes Mellitus

Bacterial infections are frequent and severe in patients with diabetes mellitus. Whether diabetes per se induces functional alterations in the complement system hampering activation during infection is unknown. We investigated key elements of the complement system during bacterial infections in pati...

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Detalles Bibliográficos
Autores principales: Barkai, László József, Sipter, Emese, Csuka, Dorottya, Prohászka, Zoltán, Pilely, Katrine, Garred, Peter, Hosszúfalusi, Nóra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436462/
https://www.ncbi.nlm.nih.gov/pubmed/30949171
http://dx.doi.org/10.3389/fimmu.2019.00509