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Recombinant Production of MFHR1, A Novel Synthetic Multitarget Complement Inhibitor, in Moss Bioreactors

The human complement system is an important part of the immune system responsible for lysis and elimination of invading microorganisms and apoptotic body cells. Improper activation of the system due to deficiency, mutations, or autoantibodies of complement regulators, mainly factor H (FH) and FH-rel...

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Detalles Bibliográficos
Autores principales: Top, Oguz, Parsons, Juliana, Bohlender, Lennard L., Michelfelder, Stefan, Kopp, Phillipp, Busch-Steenberg, Christian, Hoernstein, Sebastian N. W., Zipfel, Peter F., Häffner, Karsten, Reski, Ralf, Decker, Eva L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436476/
https://www.ncbi.nlm.nih.gov/pubmed/30949184
http://dx.doi.org/10.3389/fpls.2019.00260