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Recombinant Production of MFHR1, A Novel Synthetic Multitarget Complement Inhibitor, in Moss Bioreactors
The human complement system is an important part of the immune system responsible for lysis and elimination of invading microorganisms and apoptotic body cells. Improper activation of the system due to deficiency, mutations, or autoantibodies of complement regulators, mainly factor H (FH) and FH-rel...
Autores principales: | Top, Oguz, Parsons, Juliana, Bohlender, Lennard L., Michelfelder, Stefan, Kopp, Phillipp, Busch-Steenberg, Christian, Hoernstein, Sebastian N. W., Zipfel, Peter F., Häffner, Karsten, Reski, Ralf, Decker, Eva L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436476/ https://www.ncbi.nlm.nih.gov/pubmed/30949184 http://dx.doi.org/10.3389/fpls.2019.00260 |
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