Cargando…

Hypercapnic acidosis induces mitochondrial dysfunction and impairs the ability of mesenchymal stem cells to promote distal lung epithelial repair

Acute respiratory distress syndrome (ARDS) is a devastating disorder characterized by diffuse inflammation and edema formation. The main management strategy, low tidal volume ventilation, can be associated with the development of hypercapnic acidosis (HCA). Mesenchymal stem cells (MSCs) are a promis...

Descripción completa

Detalles Bibliográficos
Autores principales: Fergie, Nicola, Todd, Naomi, McClements, Lana, McAuley, Danny, O’Kane, Cecilia, Krasnodembskaya, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436662/
https://www.ncbi.nlm.nih.gov/pubmed/30649987
http://dx.doi.org/10.1096/fj.201802056R