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Hypercapnic acidosis induces mitochondrial dysfunction and impairs the ability of mesenchymal stem cells to promote distal lung epithelial repair
Acute respiratory distress syndrome (ARDS) is a devastating disorder characterized by diffuse inflammation and edema formation. The main management strategy, low tidal volume ventilation, can be associated with the development of hypercapnic acidosis (HCA). Mesenchymal stem cells (MSCs) are a promis...
Autores principales: | Fergie, Nicola, Todd, Naomi, McClements, Lana, McAuley, Danny, O’Kane, Cecilia, Krasnodembskaya, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Federation of American Societies for Experimental Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436662/ https://www.ncbi.nlm.nih.gov/pubmed/30649987 http://dx.doi.org/10.1096/fj.201802056R |
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