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Aqueous synthesis of a small-molecule lanthanide chelator amenable to copper-free click chemistry

The lanthanides (Ln(3+)), or rare earth elements, have proven to be useful tools for biomolecular NMR, X-ray crystallographic, and fluorescence analyses due to their unique 4f orbitals. However, their utility in biological applications has been limited because site-specific incorporation of a chelat...

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Detalles Bibliográficos
Autores principales: Bishop, Stephanie C., Winefield, Robert, Anbanandam, Asokan, Lampe, Jed N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436693/
https://www.ncbi.nlm.nih.gov/pubmed/30917122
http://dx.doi.org/10.1371/journal.pone.0209726