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Aqueous synthesis of a small-molecule lanthanide chelator amenable to copper-free click chemistry
The lanthanides (Ln(3+)), or rare earth elements, have proven to be useful tools for biomolecular NMR, X-ray crystallographic, and fluorescence analyses due to their unique 4f orbitals. However, their utility in biological applications has been limited because site-specific incorporation of a chelat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436693/ https://www.ncbi.nlm.nih.gov/pubmed/30917122 http://dx.doi.org/10.1371/journal.pone.0209726 |