Phenotype of POLE-mutated endometrial cancer

BACKGROUND AND PURPOSE: Individualized therapy in endometrial cancer, the most common gynaecologic cancer in the developed world, focuses on identifying specific molecular subtypes. Mutations in the exonuclease domain of the DNA polymerase epsilon (POLE) gene define one such subtype, which causes an...

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Detalles Bibliográficos
Autores principales: Imboden, Sara, Nastic, Denis, Ghaderi, Mehran, Rydberg, Filippa, Rau, Tilman T., Mueller, Michael D., Epstein, Elisabeth, Carlson, Joseph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436745/
https://www.ncbi.nlm.nih.gov/pubmed/30917185
http://dx.doi.org/10.1371/journal.pone.0214318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436745/
https://www.ncbi.nlm.nih.gov/pubmed/30917185
http://dx.doi.org/10.1371/journal.pone.0214318

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