Loss of function mutations in essential genes cause embryonic lethality in pigs

Lethal recessive alleles cause pre- or postnatal death in homozygous affected individuals, reducing fertility. Especially in small size domestic and wild populations, those alleles might be exposed by inbreeding, caused by matings between related parents that inherited the same recessive lethal alle...

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Detalles Bibliográficos
Autores principales: Derks, Martijn F. L., Gjuvsland, Arne B., Bosse, Mirte, Lopes, Marcos S., van Son, Maren, Harlizius, Barbara, Tan, Beatrice F., Hamland, Hanne, Grindflek, Eli, Groenen, Martien A. M., Megens, Hendrik-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436757/
https://www.ncbi.nlm.nih.gov/pubmed/30875370
http://dx.doi.org/10.1371/journal.pgen.1008055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436757/
https://www.ncbi.nlm.nih.gov/pubmed/30875370
http://dx.doi.org/10.1371/journal.pgen.1008055

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