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Powerful gene set analysis in GWAS with the Generalized Berk-Jones statistic

A common complementary strategy in Genome-Wide Association Studies (GWAS) is to perform Gene Set Analysis (GSA), which tests for the association between one phenotype of interest and an entire set of Single Nucleotide Polymorphisms (SNPs) residing in selected genes. While there exist many tools for...

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Detalles Bibliográficos
Autores principales: Sun, Ryan, Hui, Shirley, Bader, Gary D., Lin, Xihong, Kraft, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436759/
https://www.ncbi.nlm.nih.gov/pubmed/30875371
http://dx.doi.org/10.1371/journal.pgen.1007530