Cargando…

The Kinetochore-Microtubule Coupling Machinery Is Repurposed in Sensory Nervous System Morphogenesis

Dynamic coupling of microtubule ends to kinetochores, built on the centromeres of chromosomes, directs chromosome segregation during cell division. Here, we report that the evolutionarily ancient kinetochore-microtubule coupling machine, the KMN (Knl1/Mis12/Ndc80-complex) network, plays a critical r...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheerambathur, Dhanya K., Prevo, Bram, Chow, Tiffany-Lynn, Hattersley, Neil, Wang, Shaohe, Zhao, Zhiling, Kim, Taekyung, Gerson-Gurwitz, Adina, Oegema, Karen, Green, Rebecca, Desai, Arshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436928/
https://www.ncbi.nlm.nih.gov/pubmed/30827898
http://dx.doi.org/10.1016/j.devcel.2019.02.002